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Sulfotransferase

A sulfotransferase is a transferase enzyme which acts upon a sulfate group.[1] These enzymes often act to transfer a sulfate group from the coenzyme 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) to a second substrate such as a protein or lipid.[2]

They are classified under EC number 2.8.2.

An example is SULT2A1.

See also

References

  1. ^ Negishi M, Pedersen LG, Petrotchenko E, et al (2001). "Structure and function of sulfotransferases". Arch. Biochem. Biophys. 390 (2): 149–57. doi:10.1006/abbi.2001.2368. PMID 11396917. 
  2. ^ Rath VL, Verdugo D, Hemmerich S (2004). "Sulfotransferase structural biology and inhibitor discovery". Drug Discov. Today 9 (23): 1003–11. doi:10.1016/S1359-6446(04)03273-8. PMID 15574316. 

External links

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Sulfur-containing group transferases / sulfotransferases (EC 2.8)
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