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L-idonate 2-dehydrogenase

In enzymology, a L-idonate 2-dehydrogenase (EC 1.1.1.128) is an enzyme that catalyzes the chemical reaction

L-idonate + NADP⁺ 5-dehydro-D-gluconate + NADPH + H⁺

Thus, the two substrates of this enzyme are L-idonate and NADP⁺, whereas its 3 products are 5-dehydro-D-gluconate, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-idonate:NADP+ 2-oxidoreductase. Other names in common use include 5-ketogluconate 2-reductase, 5-keto-D-gluconate 2-reductase, L-idonate dehydrogenase, 5-ketogluconate 2-reductase, reductase, 5-ketogluconate 5- (L-idonate-forming), 5KGR, and 5-ketoglucono-idono-reductase.

References

• IUBMB entry for 1.1.1.128
• BRENDA references for 1.1.1.128 (Recommended.)
• PubMed references for 1.1.1.128
• PubMed Central references for 1.1.1.128
• Google Scholar references for 1.1.1.128
• Takagi Y (1962). "A new enzyme, 5-ketoglucono-idono-reductase". Agric. Biol. Chem. 26: 719–720. 

External links

The CAS registry number for this enzyme class is 37250-57-0.

• IUBMB entry for 1.1.1.128

• KEGG entry for 1.1.1.128

• BRENDA entry for 1.1.1.128

• NiceZyme view of 1.1.1.128

• EC2PDB: PDB structures for 1.1.1.128

• PRIAM entry for 1.1.1.128

• PUMA2 entry for 1.1.1.128

• IntEnz: Integrated Enzyme entry for 1.1.1.128

• MetaCyc entry for 1.1.1.128

• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0050027: L-idonate 2-dehydrogenase

• AMIGO entry for GO code 0050027: L-idonate 2-dehydrogenase