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6-methylsalicylate decarboxylase

In enzymology, a 6-methylsalicylate decarboxylase (EC 4.1.1.52) is an enzyme that catalyzes the chemical reaction

6-methylsalicylate 3-cresol + CO₂

Hence, this enzyme has one substrate, 6-methylsalicylate, and two products, 3-cresol and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 6-methylsalicylate carboxy-lyase (3-cresol-forming). Other names in common use include 6-methylsalicylic acid (2,6-cresotic acid) decarboxylase, 6-MSA decarboxylase, and 6-methylsalicylate carboxy-lyase.

References

• IUBMB entry for 4.1.1.52
• BRENDA references for 4.1.1.52 (Recommended.)
• PubMed references for 4.1.1.52
• PubMed Central references for 4.1.1.52
• Google Scholar references for 4.1.1.52
• Light RJ (1969). "6-methylsalicylic acid decarboxylase from Penicillium patulum". Biochim. Biophys. Acta. 191: 430–8. PMID 5354271. 
• Vogel G and Lynen F (1970). "6-Methylsalicylsaure-Decarboxylase". Naturwissenschaften 57: 664. 

External links

The CAS registry number for this enzyme class is 37289-50-2.

• IUBMB entry for 4.1.1.52

• KEGG entry for 4.1.1.52

• BRENDA entry for 4.1.1.52

• NiceZyme view of 4.1.1.52

• EC2PDB: PDB structures for 4.1.1.52

• PRIAM entry for 4.1.1.52

• PUMA2 entry for 4.1.1.52

• IntEnz: Integrated Enzyme entry for 4.1.1.52

• MetaCyc entry for 4.1.1.52

• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0047596: 6-methylsalicylate decarboxylase

• AMIGO entry for GO code 0047596: 6-methylsalicylate decarboxylase