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6-O-methylnorlaudanosoline 5'-O-methyltransferase

In enzymology, a 6-O-methylnorlaudanosoline 5'-O-methyltransferase (EC 2.1.1.121) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline S-adenosyl-L-homocysteine + nororientaline

Thus, the two substrates of this enzyme are S-adenosyl methionine and 6-O-methylnorlaudanosoline, whereas its two products are S-adenosylhomocysteine and nororientaline.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.

References

• IUBMB entry for 2.1.1.121
• BRENDA references for 2.1.1.121 (Recommended.)
• PubMed references for 2.1.1.121
• PubMed Central references for 2.1.1.121
• Google Scholar references for 2.1.1.121
• Rueffer M, Nagakura N, Zenk MH (1983). "A highly specific O-methyltransferase for nororientaline synthesis isolated from Argemone platyceras cell cultures". Planta Med. 49: 196–198. doi:10.1055/s-2007-969849. 

External links

The CAS registry number for this enzyme class is 89511-99-9.

• IUBMB entry for 2.1.1.121

• KEGG entry for 2.1.1.121

• BRENDA entry for 2.1.1.121

• NiceZyme view of 2.1.1.121

• EC2PDB: PDB structures for 2.1.1.121

• PRIAM entry for 2.1.1.121

• PUMA2 entry for 2.1.1.121

• IntEnz: Integrated Enzyme entry for 2.1.1.121

• MetaCyc entry for 2.1.1.121

• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0030781: 6-O-methylnorlaudanosoline 5'-O-methyltransferase

• AMIGO entry for GO code 0030781: 6-O-methylnorlaudanosoline 5'-O-methyltransferase