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4-(hydroxymethyl)benzenesulfonate dehydrogenase

In enzymology, a 4-(hydroxymethyl)benzenesulfonate dehydrogenase (EC 1.1.1.257) is an enzyme that catalyzes the chemical reaction

4-(hydroxymethyl)benzenesulfonate + NAD⁺ 4-formylbenzenesulfonate + NADH + H⁺

Thus, the two substrates of this enzyme are 4-(hydroxymethyl)benzenesulfonate and NAD⁺, whereas its 3 products are 4-formylbenzenesulfonate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase. This enzyme participates in 2,4-dichlorobenzoate degradation.

References

• IUBMB entry for 1.1.1.257
• BRENDA references for 1.1.1.257 (Recommended.)
• PubMed references for 1.1.1.257
• PubMed Central references for 1.1.1.257
• Google Scholar references for 1.1.1.257
• Cook AM (Pt 9). "Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2". Microbiology. 142: 2419–27. PMID 8828208. 

External links

The CAS registry number for this enzyme class is 167973-64-0.

• IUBMB entry for 1.1.1.257

• KEGG entry for 1.1.1.257

• BRENDA entry for 1.1.1.257

• NiceZyme view of 1.1.1.257

• EC2PDB: PDB structures for 1.1.1.257

• PRIAM entry for 1.1.1.257

• PUMA2 entry for 1.1.1.257

• IntEnz: Integrated Enzyme entry for 1.1.1.257

• MetaCyc entry for 1.1.1.257

• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0018462: 4-(hydroxymethyl)benzenesulfonate dehydrogenase

• AMIGO entry for GO code 0018462: 4-(hydroxymethyl)benzenesulfonate dehydrogenase