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4,5-dihydroxyphthalate decarboxylase

In enzymology, a 4,5-dihydroxyphthalate decarboxylase (EC 4.1.1.55) is an enzyme that catalyzes the chemical reaction

4,5-dihydroxyphthalate 3,4-dihydroxybenzoate + CO₂

Hence, this enzyme has one substrate, 4,5-dihydroxyphthalate, and two products, 3,4-dihydroxybenzoate and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming). This enzyme is also called 4,5-dihydroxyphthalate carboxy-lyase. This enzyme participates in 2,4-dichlorobenzoate degradation.

References

• IUBMB entry for 4.1.1.55
• BRENDA references for 4.1.1.55 (Recommended.)
• PubMed references for 4.1.1.55
• PubMed Central references for 4.1.1.55
• Google Scholar references for 4.1.1.55
• Ribbons DW and Evans WC (1966). "Oxidative metabolism of phthalic acid by soil pseudomonads". Biochem. J. 76: 310–318. 

External links

The CAS registry number for this enzyme class is 37290-48-5.

• IUBMB entry for 4.1.1.55

• KEGG entry for 4.1.1.55

• BRENDA entry for 4.1.1.55

• NiceZyme view of 4.1.1.55

• EC2PDB: PDB structures for 4.1.1.55

• PRIAM entry for 4.1.1.55

• PUMA2 entry for 4.1.1.55

• IntEnz: Integrated Enzyme entry for 4.1.1.55

• MetaCyc entry for 4.1.1.55

• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0018796: 4,5-dihydroxyphthalate decarboxylase

• AMIGO entry for GO code 0018796: 4,5-dihydroxyphthalate decarboxylase