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3-oxoadipate CoA-transferase

In enzymology, a 3-oxoadipate CoA-transferase (EC 2.8.3.6) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + 3-oxoadipate succinate + 3-oxoadipyl-CoA

Thus, the two substrates of this enzyme are succinyl-CoA and 3-oxoadipate, whereas its two products are succinate and 3-oxoadipyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is succinyl-CoA:3-oxoadipate CoA-transferase. Other names in common use include 3-oxoadipate coenzyme A-transferase, and 3-oxoadipate succinyl-CoA transferase. This enzyme participates in benzoate degradation via hydroxylation.

References

• IUBMB entry for 2.8.3.6
• BRENDA references for 2.8.3.6 (Recommended.)
• PubMed references for 2.8.3.6
• PubMed Central references for 2.8.3.6
• Google Scholar references for 2.8.3.6
• KATAGIRI M, HAYAISHI O (1957). "Enzymatic degradation of beta-ketoadipic acid". J. Biol. Chem. 226: 439–48. PMID 13428776. 

External links

The CAS registry number for this enzyme class is 9026-16-8.

• IUBMB entry for 2.8.3.6

• KEGG entry for 2.8.3.6

• BRENDA entry for 2.8.3.6

• NiceZyme view of 2.8.3.6

• EC2PDB: PDB structures for 2.8.3.6

• PRIAM entry for 2.8.3.6

• PUMA2 entry for 2.8.3.6

• IntEnz: Integrated Enzyme entry for 2.8.3.6

• MetaCyc entry for 2.8.3.6

• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0047569: 3-oxoadipate CoA-transferase

• AMIGO entry for GO code 0047569: 3-oxoadipate CoA-transferase