2-dehydro-3-deoxy-D-pentonate aldolase

In enzymology, a 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) is an enzyme that catalyzes the chemical reaction

2-dehydro-3-deoxy-D-pentonate pyruvate + glycolaldehyde

Hence, this enzyme has one substrate, 2-dehydro-3-deoxy-D-pentonate, and two products, pyruvate and glycolaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase (pyruvate-forming). Other names in common use include 2-keto-3-deoxy-D-pentonate aldolase, 3-deoxy-D-pentulosonic acid aldolase, and 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase. This enzyme participates in pentose and glucuronate interconversions.

References

IUBMB entry for 4.1.2.28
BRENDA references for 4.1.2.28 (Recommended.)
PubMed references for 4.1.2.28
PubMed Central references for 4.1.2.28
Google Scholar references for 4.1.2.28
Dahms AS (1974). "3-Deoxy-D-pentulosonic acid aldolase and its role in a new pathway of D-xylose degradation". Biochem. Biophys. Res. Commun. 60: 1433–9. PMID 4423285.
Dahms AS, Donald A (1982). "2-Keto-3-deoxy-d-xylonate aldolase (3-deoxy-d-pentulosonic acid aldolase)". Methods. Enzymol. 90 Pt E: 269–72. PMID 7154955.