2-Methyl-3,3-diphenyl-3-propanolamine


2-Methyl-3,3-diphenyl-3-propanolamine
Systematic (IUPAC) name
3-amino-2-methyl-1,1-di(phenyl)propan-1-ol
Identifiers
CAS number	33887-05-7
ATC code	?
PubChem	26538
Chemical data
Formula	C₁₆H₁₉N O
Mol. mass	241.33 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	Legal
Routes	?

2-MDP is a dissociative anaesthetic drug which has been found to be an NMDA antagonist and produces similar effects to PCP in animals. The levo or (-) isomer is the active form of the drug.^[1]^[2]

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

References

^ Tang AH, Cangelosi AA, Code RA, Franklin SR. Phencyclidine-like behavioral effects of 2-methyl-3,3-diphenyl-3-propanolamine (2-MDP). Pharmacology, Biochemistry and Behaviour. 1984 Feb;20(2):209-13.
^ Blake JC, Davies SN, Church J, Martin D, Lodge D. 2-Methyl-3,3-diphenyl-3-propanolamine (2-MDP) selectively antagonises N-methyl-aspartate (NMA). Pharmacology, Biochemistry and Behaviour. 1986 Jan;24(1):23-5.

v • d • e Dissociative hallucinogens

Kappa agonists	Cyclazocine - Enadoline - Salvinorin A - Pentazocine - Tifluadom

NMDA receptor antagonists	2-MDP - Dexoxadrol - Dextromethorphan - Dizocilpine - Esketamine - Etoxadrol - Ketamine - PCE - PCP - PCPy - TCP - Tiletamine

Others	Efavirenz - Muscimol - Nitrous oxide - Xenon

The original article is from Wikipedia. To view the original article please click here.
Creative Commons Licence

Custom Search