1-alkylglycerophosphocholine O-acyltransferase

In enzymology, a 1-alkylglycerophosphocholine O-acyltransferase (EC 2.3.1.63) is an enzyme that catalyzes the chemical reaction

acyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine CoA + 2-acyl-1-alkyl-sn-glycero-3-phosphocholine

Thus, the two substrates of this enzyme are acyl-CoA and 1-alkyl-sn-glycero-3-phosphocholine, whereas its two products are CoA and 2-acyl-1-alkyl-sn-glycero-3-phosphocholine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase. This enzyme participates in ether lipid metabolism.

References

IUBMB entry for 2.3.1.63
BRENDA references for 2.3.1.63 (Recommended.)
PubMed references for 2.3.1.63
PubMed Central references for 2.3.1.63
Google Scholar references for 2.3.1.63
Waku K, Nakazawa Y (Tokyo). "Acyltransferase activity to 1-O-alkyl-glycero-3-phosphorylcholine in sarcoplasmic reticulum". J. Biochem.: 459–66. PMID 5488773.
Waku K, Nakazawa Y (Tokyo). "Acyltransferae activity to 1-acyl-, 1-O-alkenyl-, and 1-O-alkyl-glycero-3-phosphorylcholine in Ehrlich ascites tumor cells". J. Biochem.: 495–7. PMID 4644313.