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1-alkenyl-2-acylglycerol choline phosphotransferase

In enzymology, a 1-alkenyl-2-acylglycerol choline phosphotransferase (EC 2.7.8.22) is an enzyme that catalyzes the chemical reaction

CDP-choline + 1-alkenyl-2-acylglycerol CMP + plasmenylcholine

Thus, the two substrates of this enzyme are CDP-choline and 1-alkenyl-2-acylglycerol, whereas its two products are CMP and plasmenylcholine.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-choline:1-alkenyl-2-acylglycerol cholinephosphotransferase. This enzyme is also called CDP-choline-1-alkenyl-2-acyl-glycerol phosphocholinetransferase. This enzyme participates in ether lipid metabolism.

References

• IUBMB entry for 2.7.8.22
• BRENDA references for 2.7.8.22 (Recommended.)
• PubMed references for 2.7.8.22
• PubMed Central references for 2.7.8.22
• Google Scholar references for 2.7.8.22
• Wientzek M, Man RY, Choy PC (1987). "Choline glycerophospholipid biosynthesis in the guinea pig heart". Biochem. Cell. Biol. 65: 860–8. PMID 3447597. 

External links

The CAS registry number for this enzyme class is 113066-36-7.

• IUBMB entry for 2.7.8.22

• KEGG entry for 2.7.8.22

• BRENDA entry for 2.7.8.22

• NiceZyme view of 2.7.8.22

• EC2PDB: PDB structures for 2.7.8.22

• PRIAM entry for 2.7.8.22

• PUMA2 entry for 2.7.8.22

• IntEnz: Integrated Enzyme entry for 2.7.8.22

• MetaCyc entry for 2.7.8.22

• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0047359: 1-alkenyl-2-acylglycerol choline phosphotransferase

• AMIGO entry for GO code 0047359: 1-alkenyl-2-acylglycerol choline phosphotransferase