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(S)-carnitine 3-dehydrogenase

In enzymology, a (S)-carnitine 3-dehydrogenase (EC 1.1.1.254) is an enzyme that catalyzes the chemical reaction

(S)-carnitine + NAD⁺ 3-dehydrocarnitine + NADH + H⁺

Thus, the two substrates of this enzyme are (S)-carnitine and NAD⁺, whereas its 3 products are 3-dehydrocarnitine, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-carnitine:NAD+ oxidoreductase.

References

• IUBMB entry for 1.1.1.254
• BRENDA references for 1.1.1.254 (Recommended.)
• PubMed references for 1.1.1.254
• PubMed Central references for 1.1.1.254
• Google Scholar references for 1.1.1.254
• Setyahadi S, Ueyama T, Arimoto T, Mori N, Kitamoto Y (1997). "Purification and properties of a new enzyme, D-carnitine dehydrogenase, from Agrobacterium sp. 525a". Biosci. Biotechnol. Biochem. 61: 1055–8. PMID 9214773. 

External links

The CAS registry number for this enzyme class is 169277-49-0.

• IUBMB entry for 1.1.1.254

• KEGG entry for 1.1.1.254

• BRENDA entry for 1.1.1.254

• NiceZyme view of 1.1.1.254

• EC2PDB: PDB structures for 1.1.1.254

• PRIAM entry for 1.1.1.254

• PUMA2 entry for 1.1.1.254

• IntEnz: Integrated Enzyme entry for 1.1.1.254

• MetaCyc entry for 1.1.1.254

• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0047041: (S)-carnitine 3-dehydrogenase

• AMIGO entry for GO code 0047041: (S)-carnitine 3-dehydrogenase