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(-)-Methyl-1-methyl-4β-(2-naphthyl)piperidine-3β-carboxylate

(-)-Methyl-1-methyl-4β-(2-naphthyl)piperidine-3β-carboxylate
Systematic (IUPAC) name
methyl (3S,4S)-1-methyl-4-naphthalen-2-ylpiperidine-3-carboxylate
Identifiers
CAS number  ?
ATC code  ?
PubChem 10684403
Chemical data
Formula C18H21NO2 
Mol. mass 283.364
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

(-)-Methyl-1-methyl-4β-(2-naphthyl)piperidine-3β-carboxylate is a piperidine based stimulant drug which is synthesised from arecoline. It is similar to nocaine in chemical structure, and has and a half times more activity than cocaine as a dopamine reuptake inhibitor. However it is also a potent serotonin reuptake inhibitor, with similar affinity to fluoxetine.[1] It is a structural isomer of another potent dopamine reuptake inhibitor, HDMP-28.

References

  1. ^ Further SAR Studies of Piperidine-Based Analogues of Cocaine. 2. Potent Dopamine and Serotonin Reuptake Inhibitors. Retrieved on 2008-01-11.

See also


 This pharmacology-related article is a stub. You can help Wikipedia by expanding it.
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Stimulants
Alkylamines
Cyclopentamine • Geranamine • Isometheptene • Octodrine • Propylhexedrine • Tuamine
Alphapyrrolidinylalkiophenones

α-PPP • MDPPP • MDPV • MPHP • MPPP • MOPPP • Pyrovalerone
Cholinergics
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Eugeroics
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4-Bromomethcathinone • 4-Fluoroamphetamine • 4-Fluoromethamphetamine • 4-Fluoromethcathinone • 4-Methylmethcathinone • 4-MTA • Aletamine • Amfepentorex • Amphechloral • Amphetamine (Dextroamphetamine, Adderall) • Amphetaminil • Benzphetamine • Bupropion • Cathinone • Chlorphentermine • Clenbuterol • Clobenzorex • Clortermine • Diethylpropion • Dimethoxyamphetamine • Dimethylamphetamine • Dimethylcathinone • Ephedrine • Epinephrine • Ethcathinone • Ethylamphetamine • Fenethylline • Fenfluramine • Fenproporex • Furfenorex • Levomethamphetamine • Lisdexamfetamine • MDMA • Mefenorex • Methamphetamine • Methcathinone • Methoxyphedrine • Methylone • Octopamine • Parahydroxyamphetamine • PCA • PIA • PMA • PMEA • PMMA • PPAP • Phendimetrazine • Phenmetrazine • Phentermine • Phenylephrine • Phenylpropanolamine • Propylamphetamine • Pseudoephedrine • Selegiline • Synephrine • Xylopropamine
Phenylaminooxazoles
Piperazines

2C-B-BZP • BZP • GBR-12783 • GBR-12935 • GBR-13069 • GBR-13098 • GBR-13119 • MeOPP • MBZP • Vanoxerine
Piperidines

2-Benzylpiperidine • Desoxypipradrol • Ethylphenidate • HDMP-28 • (-)-Methyl-1-methyl-4β-(2-naphthyl)piperidine-3β-carboxylate • Methylphenidate (Dexmethylphenidate) • Nocaine • Phacetoperane • Pipradrol
Tropanes

3-Pseudotropyl-4-fluorobenzoate • Altropane • Brasofensine • CFT (WIN 35,428) • β-CIT (RTI-55) • Cocaethylene • Cocaine • β-CPPIT • Dichloropane (RTI-111) • Difluoropine • FE-β-CPPIT • FP-β-CPPIT • PIT • PTT • RTI-31 • RTI-32 • RTI-51 • RTI-112 • RTI-113 • RTI-121 (IPCIT) • RTI-126 • RTI-150 • RTI-171 • RTI-177 • RTI-336 • Tesofensine • Troparil (β-CPT, WIN 35,065-2) • WF-23 • WF-33 • WF-60
Xanthines
Others
See also Sympathomimetic amines
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