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(+)-neomenthol dehydrogenase

In enzymology, a (+)-neomenthol dehydrogenase (EC 1.1.1.208) is an enzyme that catalyzes the chemical reaction

(+)-neomenthol + NADP⁺ (-)-menthone + NADPH + H⁺

Thus, the two substrates of this enzyme are (+)-neomenthol and NADP⁺, whereas its 3 products are (-)-menthone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+)-neomenthol:NADP+ oxidoreductase. This enzyme is also called monoterpenoid dehydrogenase. This enzyme participates in monoterpenoid biosynthesis.

References

• IUBMB entry for 1.1.1.208
• BRENDA references for 1.1.1.208 (Recommended.)
• PubMed references for 1.1.1.208
• PubMed Central references for 1.1.1.208
• Google Scholar references for 1.1.1.208
• Kjonaas R, Martinkus-Taylor C and Croteau R (1982). "Metabolism of monoterpenes: conversion of l-menthone to l-menthol and d-neomenthol by stereospecific dehydrogenases from peppermint (Mentha piperita) leaves". Plant Physiol. 69: 1013–1017. 

External links

The CAS registry number for this enzyme class is 81811-47-4.

• IUBMB entry for 1.1.1.208

• KEGG entry for 1.1.1.208

• BRENDA entry for 1.1.1.208

• NiceZyme view of 1.1.1.208

• EC2PDB: PDB structures for 1.1.1.208

• PRIAM entry for 1.1.1.208

• PUMA2 entry for 1.1.1.208

• IntEnz: Integrated Enzyme entry for 1.1.1.208

• MetaCyc entry for 1.1.1.208

• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0047501: (+)-neomenthol dehydrogenase

• AMIGO entry for GO code 0047501: (+)-neomenthol dehydrogenase